主编领导Prof Insup Noh,Biomaterials Researchhas recently reached its first anniversary of being published by BioMed Central. Furthermore,Biomaterials Research很高兴欢迎八名新成员加入编辑委员会，在这里，我们向其中三个询问了他们的生物材料研究领域的发展。
Ren-ke li, Canada
Ren-ke是多伦多总研究所的高级科学家，也是多伦多大学心血管手术教授。1996年，他首次证明了移植的心肌细胞可以改善心脏功能。他提出“恢复活力”作为老年患者干细胞疗法的新概念。
What are the roles of biomaterials in rejuvenation and how can we use it to improve the stem cell therapy for aged patients?
Cells, including stem cells, live in their perfect microenvironments and function as directed by surrounding signals. Aging causes the dysfunction of cells, and most importantly is due to the alteration of the microenvironment.
恢复衰老细胞的一种方法是改变其细胞微环境。生物材料和组织工程是创建微环境改变细胞功能的理想技术。我们已经表明，适当的微米元素能够增强源自老年患者的细胞的细胞功能，从而诱导“恢复活力”。
加拿大杰克·巴拉莱特
As Vice Chair of Research, Department of Surgery and Professor in the Faculties of Medicine and Dentistry at McGill University, Jake specializes in bioceramics, in particular; low temperature syntheses of nanocrystalline and amorphous inorganics, cold setting materials (cements) and precipitation to create new or improved materials or devices for tissue repair or delivery.
生物陶瓷对世界各地人们生活的影响是什么？
Of course bone fillers, scaffolds, ceramic crowns, ceramic prosthesis bearings and plasma sprayed coatings flash through most people’s mind. They have indeed all had tremendous impact on improving quality of life and arguably in essentially creating the biomaterials field of material-tissue interactions.
我认为可以说，尽管磷酸钙在蛋白质纯化中的原始工业规模使用，例如在抗体生产中，肥料，使有毒的土壤污染物相对不溶性甚至是片剂的赋形剂，可能会触及全球更多人的生活。
It is from and to these applications where we can apply our interdisciplinary skills to bear on improving existing materials and developing new ones. The use of titanium in orthopaedic and oral surgery is ubiquitous but isn’t it titanium oxide that gives it its bone bonding ability?
Not only the intentional use of bioceramics, but their prevalent pathological formation sadly touches many of our lives and there is huge need for us to help control this unwanted biomineralisation.
Bioceramics研究人员是从有限的“成分”清单（主要是磷酸盐，碳酸盐，硫酸盐，硅酸盐和氧化物）中创建新物业的专家，并使用无毒的和通常的低温处理途径遵守监管立法。
These skills are increasingly in demand by industry needing to produce inorganics while complying with new environmental legislation and minimizing high energy consumption. The beneficial impact of bioceramics research then can only affect more people globally in the future and only just recently Korean labs turned磷成2D导体。
One thing is for sure; there will be many new applications and opportunities as bioceramics materials chemistry continues to evolve.
Dan Peer,Israel
Dan是以色列特拉维夫大学的纳米医学实验室教授。他及其同事成功地开发了“癌症子弹”系统，这是一种基于纳米颗粒的治疗方法，用于靶向癌细胞。
How effective is nanomedicine in treating cancer?
This is a tricky question. There have been a lot of activities with numerous strategies being developed (currently more than 250 clinical trials at different stages with different strategies) and more than 30 nanomedicines already in clinical practice. These range back from 1995 with the first FDA approved liposomal Doxorubicin (DOXIL) to today.
Still, there are numerous challenges that need to be overcome in order to show superior efficacy and improve toxicity profile compared with free drugs. This is true for solid tumors which represent more than 80% of cancers but also for blood cancers (a group of 57 diseases including lymphoma, leukemia and myeloma).
Thus, still basic research and translational work is essential in order to better understand biological and pathological barriers, tumor heterogeneity and the abilities of different strategies to really make an impact on cancer patients’ lives by improving the efficacies of treatments and decreasing the drug toxicity without introducing new types of toxicities.
What are the roles of biomaterials in nano-level?
产生新的生物材料确实可以使有毒配方与成功的治疗方法和卓越治疗之间的一种不同。因此，在纳米级别，生物材料可以为治疗和诊断策略开放新的途径，并会影响癌症诊断和治疗剂（甚至是治疗剂）（甚至是治疗剂）等领域，以及炎症性疾病，包括神经退行性疾病，炎症性肠道疾病和许多自身疾病，sepiss和许多自身疾病，SESPIS，SESPIS和许多自身疾病。
我们还想欢迎以下新的board members：彼得·杜布雷尔（Peter Dubruel）（比利时），冯·休伊（Feng-Huei Lin）（台湾），JoanaMagalhães（西班牙），Abhay S Pandit（爱尔兰）和Murugan Ramalingam（印度）。
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