The Great Wall is one of the most famous icons in China. The original purpose of building it was to protect China against the raids and invasions of the various nomadic groups of the Eurasian Steppe. In the human body, our immune system is similar to the Great Wall in order to protect human beings against various diseases.
Immunology is an important subject that studies all aspects of the immune system and has direct relations to human health and diseases. The subject has been growing very fast in China over the past five years.
免疫学领域
由中国科学家贡献的免疫学研究领域的出版物数量从2010年的1771年增长到2014年的3199年，现在中国在2014年免疫学科学出版物数量上排名第二。
从2010年到2014年，中国免疫学出版物的复合年增长率为16％，在同一时期的开放访问模型下，增长率为43％。This indicates that more and more Chinese immunologists prefer to publish their research in open access journals.
从2010年到2014年，中国免疫学出版物的复合年增长率为16％，在同一时期的开放访问模型下，增长率为43％。
In the early winter this year, the 10th中国免疫学会年会was held in Beijing and many top Chinese and international immunologists gathered together to discuss their latest findings and the future trend of immunology.
As the old friend of Chinese Society for Immunology, BioMed Central held a booth at this conference and had discussions with many attendees. In the three days of the conference, eight big themes were intensively discussed, including; the differentiation and development of immune cells, the identification and regulation of innate immune responses, immunodeficiency diseases and allergic diseases, mechanisms of immune regulation and tolerance, transplantation immunity, infection immunity, autoimmune diseases, tumor immunity and tumor immunotherapy.
Research highlights discussed at the conference
中国医学科学院校长Xuetao Cao教授介绍了他最近关于先天免疫和炎症的法规模式的研究。CAO教授说，模式识别受体（PRR）的结构和功能研究是过去十年中的热门话题，这引起了许多重要的研究进展。
Recently, the mechanistic study from an epigenetic angle of PPR regulation mode is receiving more and more attention and Professor Cao’s team has made some significant discoveries in this field.
He found that the decisive factor in the regression of inflammation is the epigenetic regulation rather than the negative regulation of signal transduction. This research has profound significance in the treatment of autoimmune and inflammation related diseases.
中国免疫学协会主席齐贡·蒂（Zhigang Tian）教授发表了题为“抑制抑制受体tigit的封锁，阻止了抗肿瘤NK细胞疲惫”。
中国免疫学协会主席齐贡·蒂（Zhigang Tian）教授发表了题为“抑制抑制受体tigit的封锁，阻止了抗肿瘤NK细胞疲惫”。他的演讲表明，在肿瘤进展过程中，T细胞IG和ITIM结构域（Tigit）是在T细胞和NK细胞上表达的共抑制受体。
His team discovered that the growth and metastasis of pre-established B16/F10 tumor in mice could be suppressed by blocking TIGIT signaling in vivo via monoclonal antibodies in combination with Flt3L overexpression in vivo by gene delivery.
还发现该方法可有效抑制结肠癌，乳腺癌和MCA诱导的体内纤维肉瘤的生长。这些发现表明，Tigit有助于肿瘤诱导的免疫衰竭，可能是癌症免疫疗法的有希望的靶标。
Professor Yuzhang Wu, the Director of Institute of immunology, PLA talked about how the TCF-1 transcription factor initiated the differentiation of follicular helper T cells (TFHcells) during acute viral infection.
他的团队发现TCF-1在启动T的差异化方面发挥了关键作用FH和developing the effector function of the differentiated TFHcells during acute viral infection, as well as disclosed the mechanism of such process.
Wu教授最终总结说，TCF-1是BCl-6-Blimp 1轴上游的重要枢纽，可以启动和确保t的区分FH急性病毒感染的细胞。
开放访问免疫学
演讲结束后，吴教授分享了他在开放访问出版方面的经验和愿景。他说，开放访问将是未来科学出版的主要趋势和可持续模型。
在免疫学社区中讨论了许多免疫学上令人惊叹的科学发现，我们认为这将提高该领域的进步，并可能具有改善人类社会健康状况的巨大潜力。
During the three days, many amazing scientific findings in immunology were discussed in the community of immunology, which we believe would advance the progress of this field and might have huge potentials to improve the health conditions of human society, such as generating solutions to nowadays incurable diseases.
BioMed Central, as the first open access publisher, holds a strong portfolio of immunology journals, such asAllergy, Asthma & Clinical Immunology,BMC Immunology,炎症杂志,Journal of Neuroinflammation,艾滋病研究和治疗和Immunity & Ageing.
这次会议的许多与会者都来了我们的展位，并与我们讨论了他们在期刊上发表研究时的故事，并向我们的出版服务提供了宝贵的建议。
在这里,我们感谢所有的人。我们想说的that our only aim is to provide the best services to our authors in publishing their latest scientific findings, as well as to provide our readers the best experiences in reading scientific articles through our PC and mobile platforms.
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