口腔,头颈癌宣传月:研究重点

BMC在4月的4月7日开始,在4月7日开始,由头颈癌联盟(Head Heart and Neck Cancer Alliance)领导,在4月份为口腔和颈部癌症宣传月提供了支持。在此博客中,我们的编辑重点介绍了有关口服,头颈癌的最新发展和新兴研究领域。今年,我们也创建了测验补充这些亮点和我们的作者博客讲话通常持有头颈癌的神话

头颈癌占美国和欧洲所有癌症的5-10%。Oral, head and neck cancers are categorized by where they originate: either in squamous cells that line the head and neck or in the salivary glands. These cancers are then again subcategorized by the physical anatomy of where the cancer resides. An even more unique distinction is a sub-classification of head and neck cancers that is defined by an infection, Human Papillomavirus (HPV)-initiated oropharynx cancer. TheseHPV相关的癌症代表不同的疾病具有不同的病因,治疗策略和分子分析。这一研究领域正在迅速发展,新发现和挑战。我们打算影响口腔,头颈癌的研究和临床护理方向。

以下是我们的开放访问期刊中按方法和亚型主题分类的最新文章的集合:应用癌症研究,,,,性别差异的生物学,,,,BMC癌,,,,癌细胞国际,,,,Cancer Imaging,,,,Cancers of the Head & Neck,,,,细胞死亡与疾病,,,,临床表观遗传学,,,,Clinical Proteomics,,,,头和脸部药,,,,Human Genomics,,,,传染性药物和癌症,,,,Insights into Imaging,,,,实验与临床癌症研究杂志,,,,血液学和肿瘤学杂志,,,,耳鼻喉科学杂志:头颈外科手术,健康与疾病的脂质,,,,orphanet稀有疾病杂志,,,,辐射肿瘤学

全世界人们都在通过数千种活动来帮助传播这些信息。使用#Ohancaw标签加入本月的活动。

HPVinfections and cancers

马来西亚口咽鳞状细胞癌的临床病理特征,参考HPV感染

High-risk type human papillomavirus infection and p16 expression in laryngeal cancer

HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis

Human papillomavirus genome variants and head and neck cancers: a perspective

Locally advanced high-risk HPV related oropharyngeal squamous cell carcinoma (OPSCC); have we forgotten it is a different disease?

口服癌

Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells

Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma

Sex differences in patients with high risk HPV-associated and HPV negative oropharyngeal and oral cavity squamous cell carcinomas

基于金纳米颗粒的血清表面增强拉曼光谱,用于诊断口腔鳞状细胞癌

Treatment of oral cancers during pregnancy: a case-based discussion

© alessandroguerriero / Getty Images / iStock

预后评估和生物标志物

Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands

淋巴结疾病预测复发,而其他传统因素会影响南非分化患者队列中的生存率

头颈癌患者中循环白细胞介素-6水平的预测指标

口服鳞状细胞癌中磷脂酰肌醇3-激酶/AKT信号通路的预后意义:P-MTOR的过表达表明不良预后

Relation of baseline neutrophil-to-lymphocyte ratio to survival and toxicity in head and neck cancer patients treated with (chemo-) radiation

β-catenin,TCF-4和Survivin在鼻咽癌中的作用:与临床病理学特征的相关性和预后意义

Salvage radiotherapy for recurrent hypopharyngeal and laryngeal squamous cell carcinoma (SCC) after first-line treatment with surgery alone: a 10-year single-centre experience

乌干达坎帕拉Mulago医院口服鳞状细胞癌(OSCC)患者的生存和相关因素

2D和3D细胞培养物对头部和颈部癌中治疗反应,EMT谱和干细胞特征的影响

表观遗传学,基因组学和高通量技术

综合数据分析揭示了乳头状甲状腺癌中DNA甲基化破坏的潜在驱动因素和途径

PDX模型中的综合基因组分析揭示了细胞周期蛋白依赖性激酶抑制剂palbociclib作为鼻咽癌的新型候选药物

对口咽鳞状细胞癌表观遗传驱动因素的新见解:HPV和生活方式因素的作用

X染色体协会研究揭示了鼻咽癌的遗传敏感性基因座

Lifestyle habits and risk factors

Compared characteristics of current vs. past smokers at the time of diagnosis of a first-time lung or head and neck cancer: a cross-sectional study

调查头颈癌患者遵守澳大利亚营养护理指南

航空公司驾驶舱和机舱船员的甲状腺癌风险:一项荟萃分析

Risk assessments and diagnostics: imaging and screening

Easily detected signs of perineural tumour spread in head and neck cancer

肿瘤头和颈部成像中的FDG-PET/CT陷阱

全基因组DNA甲基化谱鉴定了印度口服鳞状细胞癌患者中独特的一组差异甲基化的免疫基因

Multimodality imaging of paragangliomas of the head and neck

MRI直方图和纹理分析的效用,用于预测头部和颈部恶性肿瘤的组织学诊断

Clinical trials and immunotherapy strategies

©vege / stock.adobe.com

3-weekly or weekly cisplatin concurrently with radiotherapy for patients with squamous cell carcinoma of the head and neck – a multicentre, retrospective analysis

在样本大小限制下提供最佳证据的请求:在法科诺尼贫血患者中解决白细胞和红细胞洛基亚的吡格列酮的例子

羰基还原酶1是改善放射疗法对头部和颈部鳞状细胞癌作用的新目标

Durvalumab的I/II期试验以及转移性头部和颈部癌的立体定向身体放射疗法

Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck – clinical results from the cohort of the clinical cooperation group “Personalized Radiotherapy in Head and Neck Cancer”

Serum proteomic-based analysis identifying autoantibodies against PRDX2 and PRDX3 as potential diagnostic biomarkers in nasopharyngeal carcinoma

Targeting phosphoinositide 3-kinase (PI3K) in head and neck squamous cell carcinoma (HNSCC)

Ultrasound-guided percutaneous laser ablation for papillary thyroid microcarcinoma: a retrospective analysis of 37 patients

治疗方法

EGCG介导的HEPG2细胞中AFP自噬调制的一种新分子机制

Accelerated vs. conventionally fractionated adjuvant radiotherapy in high-risk head and neck cancer: a meta-analysis

通过使用多功能纳米颗粒的saracatinib靶向SRC来对抗头颈癌转移

DACH1对喉鳞状细胞癌的增殖和侵袭的影响

Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis

Trans-vaccenic acid inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via a mitochondrial-mediated apoptosis pathway

Patient care and quality of life

将认知行为疗法技术与头颈癌吞咽困难的吞咽治疗相结合的可行性和可接受性

Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: a cluster preference randomized controlled trial

进步的阻力训练极瘦弱的头和脖子cancer patients undergoing radiotherapy: a randomized controlled pilot feasibility trial

时间足够长的时间对于那些使用它的人

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