与Olga Golubnitschaja教授的问答:预测,预防和个性化医学

预测、预防和个体化医学(PPPM) means a new culture and an advanced multi-professional approach focused on individual needs of healthy people and patients providing cost-effective solutions for healthcare system as the whole. EPMA (the European Association for Predictive, Preventive and Personalised Medicine) have recently released guidelines and expert recommendations on the importance of shifting healthcare towards PPPM. In this Q&A, first author of the paper and Editor-in-Chief forEPMA Journal,Olga Golubnitschaja教授向我们介绍了此问题的重要性。

请您能告诉我们一些有关欧洲预测,预防性和个性化医学协会以及提出此职位声明的工作组的信息吗?

Olga Golubnitschaja教授
Olga Golubnitschaja教授

EPMA(EPMA(www.epmanet.eu)with 47 country members (Europe and world-wide), was created in 2008 in order to promote a paradigm shift away from “unPPPM” which is characterised by delayed intervention, untargeted medication, overdosed patients, and ineffective treatments to predictive, preventive and personalised medicine (PPPM) in medical sciences and healthcare systems on the European and global scale.

由于其具有多方面的优势(例如患者的明确概念和优势,多专业方法,出色的技术创新和医疗保健的先进经济),PPPM被认为是未来的医学。

创建EPMA职位论文2016的专门工作组由专家组成,积极参与世界领先的组织,科学团体和医疗中心,这些专业中心的专业知识从传统医学到创新技术,医学伦理,法律,法律和医疗保健经济。

请您总结您希望在您的职位声明中传达的关键发现吗?

医学的道德要求是确定正确的患者,在正确的时间用正确的药物治疗和正确的剂量

Several approaches have been suggested in ancient and modern medicine to conduct medical services in an optimal way. Currently there are too many different names of medicine, frequently confusing patients and even professionals. What is the difference between ‘Person-centred’, ‘Individualised’, ‘Stratified’, and ‘Precision’ medicine, amongst others? How big is the potential beyond corresponding approach to satisfy the needs of the individual, the patient, professional groups involved and society at large?

专门的EPMA工作组对问题进行了深入分析,然后考虑到“疾病护理”和“医疗保健”实践的多方面方面的专家建议。结论和建议总结在本文中列出的表1中。在下面成像,最佳系统在全球范围内有效地推进了医疗保健系统。

范式从“反应性”转变为“预测,预防和个性化医学”
范式从“反应性”转变为“预测,预防和个性化医学”

为什么这是医疗保健未来的重要话题?

医学的道德要求是确定正确的患者,在正确的时间用正确的药物治疗和正确的剂量。However, good but empty slogans are not helpful – they should be achievable and this requires a feasible approach.

患有实际或潜在疾病的公民想要一种在中心的药物,该药物是针对其个体患者概况量身定制的,一种能够预测和预防可能疾病的药物。他们对这种药物的实际分类术语不感兴趣。但是,他们对药物分类的推理感兴趣,以欣赏其恢复健康的潜在能力。这是在预测,预防和个性化医学方面说话的真正优势:患者了解发生了什么!

PPPM将自己借给了一个超大型伞,根据该保护措施,当代生物医学的主要道德问题可以得到积极解决。当然,一种预测性和预防方法可能意味着几个道德问题。例如:过度诊断和过度治疗;检测偶然发现;心理负担和严重的存在选择,与疾病的潜力相关,使我们的后代传播到我们的后代。

在上下文上,PPPM是为实际或潜在患者提供的认真道德咨询的最佳医学合作伙伴的关键作用,以便使他们能够对诊断,监视或治疗途径做出明智的选择;尤其是当这些路径与必须解决的道德或存在问题情况相交时。

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