血癌意识月:突出我们的开放进入血液癌研究

为了标记血液癌症的认识月份,我们的编辑跨越了许多开放式肿瘤学期刊已经开发了一系列文章,以展示该领域的一些最新研究。我们还创造了一个blood cancer morphology quiz帮助可视化不同类型的血液癌症。让我们知道您对研究或测验的看法@OncoBioMed#BloodCancerAwarenessMonth.

九月标志着血癌的认识月。为了认识到这一点,我们很自豪能够展示我们对血症癌症的一些研究,这些癌症已在公开进入肿瘤学期刊投资组合中发表。

血癌encompasses many different hematological disorders that affect the blood, bone marrow and/or lymphatic system. The different types of blood cancer can be grouped into the following categories: leukemia, lymphoma or myeloma. It is estimated that in the US, a person is diagnosed with blood cancer每三分钟一次。Leukemia is a global problem and is currently ranked the13.最常见的癌症worldwide.

如果您想回到基础知识,并概述血液癌的分类和实验室调查,请点击此处阅读我们的“血癌in a nutshell: Classification and investigation' 博客。

As a global health issue, continued research on blood cancer is of paramount significance with particular reference to risk assessment and prognostics, diagnostics, genetics, clinical trials and therapeutics. The articles in this collection have been curated by our oncology journal editors and include some of the latest research in the field in each of these categories.

Risk assessment and prognostics

© Juan Gärtner / Fotolia

血清免轻链与慢性淋巴细胞白血病和单克隆B细胞淋巴细胞增长的关联

Clinical predictors of long-term survival in newly diagnosed transplant eligible multiple myeloma — an IMWG Research Project

Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine

急性髓性白血病(AML)的晚期复发:克隆演化或治疗相关的白血病?

Management of cardiovascular risk in patients with multiple myeloma

Polyclonal serum free light chain elevation is associated with increased risk of monoclonal gammopathies

对最小残留疾病的评估与细胞突变预测急性髓性白血病患者的结果

诊断

©rosshelen / getty图片/ iStock

引入新一代的挑战sequencing (NGS) for diagnostics of myeloid malignancies into clinical routine use

来自高风险慢性淋巴细胞白血病系群的亲属增加了IgM和异常的自由轻链比

鉴定ADGRE5作为鉴别Burkitt淋巴瘤与弥漫性大B细胞淋巴瘤的Myc靶标

诊断的淋巴细胞症在骨髓增生综合征中具有高度普遍的普遍性,并且在IPSS-R低风险患者中具有独立的负预测值

Molecular tumor analysis and liquid biopsy: a feasibility investigation analyzing circulating tumor DNA in patients with central nervous system lymphomas

Micrornas,Circrnas和长的非致rNA在急性髓性白血病中的作用

血液恶性肿瘤中的T细胞衰老和Car-T细胞耗尽

Genetics

©kttyage / getty图片/ iStock

A modular transcriptome map of mature B cell lymphomas

Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome

一种基于年龄的RNA表达范式,用于存活生物标志物鉴定儿科神经母细胞瘤和急性淋巴细胞白血病

解密多发性骨髓瘤中拷贝数改变的年表

明显的启动子甲基化型剖面显示出2例骨髓瘤患者的空间表观遗传异质性,多焦点复发

多发性骨髓瘤MiR-340-5P的表观遗传沉默:机制和预后影响

Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

对瓜达替滨复发/难治性急性髓性白血病的基因组和表观脑瘤度预测因子

儿童急性淋巴细胞白血病幸存者心肺体育健康与培训基因的遗传关联鉴定

Immunoglobulin gene rearrangement IGHV3-48 is a predictive marker of histological transformation into aggressive lymphoma in follicular lymphomas

Long non-coding RNAs in hematological malignancies: translating basic techniques into diagnostic and therapeutic strategies

Mutational processes contributing to the development of multiple myeloma

The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

Clinical trials

© David A Litman / stock.adobe.com

A randomised phase II trial of selinexor with cyclophosphamide and prednisolone in relapsed or refractory multiple myeloma (RRMM) patients

解释多发性骨髓瘤中的临床试验数据:将调查结果转化为真实世界的环境

PERCEPT – myeloma transplant prehab study

RIVA - 一种重复或难治性B细胞恶性肿瘤中rituximab和varlilumab的IIa研究:用于随机对照试验的研究方案

疗法

© peterschreiber.media / stock.adobe.com

多发性骨髓瘤自体干细胞移植的现状

EzH2作为多发性骨髓瘤和其他血液恶性肿瘤的治疗靶标

Functional diversity of inhibitors tackling the differentiation blockage of MLL-rearranged leukemia

inotuzumab ozogamicin在急性淋巴细胞白血病和非霍奇金淋巴瘤的临床开发中

通过评估弥漫性大B细胞淋巴瘤治疗计划中的原产地的细胞集成精度药物

Micafungin prophylaxis for acute leukemia patients undergoing induction chemotherapy

Novel and emerging therapies for B cell lymphoma

超级增强剂:血液学恶性肿瘤中的关键作用和治疗靶标

针对CLL-1用于急性髓性白血病治疗

汽车T细胞治疗之旅:复发或难治性的儿科和年轻成人经验


Articles from the following journals have been included in this collection:Biomarker Research/BMC癌症/癌细胞国际/Clinical Epigenetics/血癌杂志/基因组医学/ISRCTN Registry/Journal of Hematology & Oncology/Trials

现在你已经阅读了这项研究,为什么不测试你对血癌形态的了解Blood Cancer Quiz

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